Human Genetics (4) Gene mapping in humans; molecular basis of genetic disease; genomic structure; immunogenetics; and genetic evidence for human evolutionary history.
ANTH (BIOL) 460H Human Genetics (4)
Students will explore interesting normal or pathological variation to understand first its biological nature, then its epidemiological distribution, genes and genetic mechanisms associated with the trait, phylogenetic origins or comparison, and the nature of relevant genotype-phenotype relationships. Alternatively, students may explore methods for identifying and characterizing gene action or structure, or historical subjects related to human variation and evolution. Ethical and societal aspects of these issues will be considered as well. Time will be taken for faculty or students to read and present current important papers appearing in the literature, relevant to the current course topics. As an Honors course, we will have the time, and the students the dedication, to pursue the chosen topic(s) in much greater and more rigorous detail than is possible in the usual lecture or even seminar course format of Human Genetics 460 which, while presenting material at a sophisticated level, will not have time to explore the more subtle, problematic, or challenging aspects. The students who enroll for this course will be given a description of the approach and the intended general topic, on a course web page or by email when the instructor learns they have registered. The nature of the course will be described including semester-specific themes or focus that will apply (if any). Requisite background reading will be identified so students will know what will be expected of them. Some prior reading will be assigned, so that we can begin the semester with a common basis in background. Students will be evaluated on the quality of their project work, including writing ability, presentation ability, and depth of thought. Several written assignments will be given and graded for content and expression quality. Although students will take regular Human Genetics 460 lectures, they may be given separate exams (corresponding to those given in the regular course) that will allow more freedom of expression than multiple-choice exams or homework assignments. Depending on the workload in any semester, there may be a separate written take home synthetic essay final exam. The Honors session each week will be highly interactive rather than passive, and students will be graded on attendance, participation and whether they have done assigned work in advance of the class. Students will be expected to have the stipulated background knowledge of biological anthropology, evolutionary biology, statistics and genetics. This course should count as 4 credits toward additional courses in biological anthropology required for the Anthropology major.
Note : Class size, frequency of offering, and evaluation methods will vary by location and instructor. For these details check the specific course syllabus.