Biological Chemistry (3) Fundamentals of Biochemistry for Chemists. Students cannot receive credit for both CHEM 476 and B M B 401.
CHEM 476 Biological Chemistry (3)
Approximately a quarter of the course will be devoted to a description of the structure and chemical properties of biomolecules. Another quarter will focus on physical processes such as reaction kinetics and binding equilibria. The third part will present some of the chemical logic in enzymatic reactions, drawing from advanced organic and inorganic chemistry concepts. The last part will address energetic aspects of metabolism. Throughout, the approach will be to introduce the analytical tools that have led to major advances in biochemistry as well as the physical and chemical principles underlying each topic. For example, in the presentation of the structure of DNA, the techniques of X-ray diffraction, sedimentation, and optical spectroscopy, will be reviewed. In the discussion of enzyme kinetics, fluorescence and stopped-flow equipment will be described, etc. The course will follow a textbook designed for chemistry students. It will also include reading assignments of several types: historical papers, current scientific literature (breakthrough reported in the journals SCIENCE and NATURE), and current biological science and society topics, as presented in Science Times section of the New York Times. Review sessions with three-dimensional graphic presentation of structures will be organized (these have been successful at demonstrating the complexity and beauty of biomolecules). The course also includes assignments that require of the students that they use databases such as those of the National Center for Biotechnology Information.
Note : Class size, frequency of offering, and evaluation methods will vary by location and instructor. For these details check the specific course syllabus.