Skip Navigation
search: People Opens New Window | Departments Opens New Window | Penn State Opens New Window | Web Opens New Window
Penn State mark
Penn State mark
University Bulletin
Undergraduate Degree Programs

These course descriptions are not being updated as of August 1, 2016. Current course descriptions are maintained in LionPATH.

Materials Science and Engineering (MATSE)

MATSE 403 (BME 443) Biomedical Materials (3) Describe properties of materials and composites and their in vivo interactions.

MATSE 403 (BIOE 443) Biomedical Materials (3)

Metals, polymers, and ceramics, and their composites, which are capable of emulating the functions of hard and soft tissues, are the subjects of this course.‘The subject matter shall be confined to implanted materials; external appliances, such as casts, braces, etc are not considered The topical content of this course will be grouped into four areas. A general introduction to selected aspects of physiology will be presented. This will provide the background necessary to appreciate the factors which govern the selection of biomedical materials. Specific emphases will be placed on polymerization of biopolymers (polypeptides and polysaccharides) and the general relationships between conformation and biological function, the biochemistry of blood and blood surface interactions, the formation of teeth and bone and the relationships between microstructure, composition and function, the immune responses to implanted materials, the resorption of bone (osteoporosis) and the development of caries. The perspective placed on these topics will be that of materials science. ‘The selection of ceramics for hard tissue prosthesis will be discussed. Orthopaedic and dental applications for ceramics will be discussed. Specific ceramic materials to be treated include dental porcelain, alumina- and zirconia-based ceramics, and bioglasses and pyrolytic carbons. Various classes of inorganic cements, gypsum, zinc phosphates, zinc carboxylates, silicates, and glassionomer cements will also be considered as ceramics. Hydroxyapatite, Hap-based composites and Hap-metal interactions will be discussed in particular Relationships among physical properties, mechanical properties, and chemical interactions with biological fluids will be described. Dental and orthopedic applications of metals will be described. The fracture toughness of metals, their electrochemical responses in vivo, and the nature of the interfacial interactions with hard tissues will be treated Dental amalgams and the noble metals for dental applications will be considered. Metals and alloys, such as Ti, Co-Cr, and vitallium, used in prosthetic applications, will be described and their properties and limitations discussed The phenomenon of stress shielding and the immune responses associated with the accumulation of metallic and polymeric particular debris in the vicinity of an implant will be discussed in particular Polymeric materials are important in a broad range of biomedical applications. Among these are soft tissue prostheses, hemostatic agents, dental restoratives, bone replacement materials, and surgical adhesives. In some applications it is desirable that a polymeric material biodegrade while in others property retention is desirable.

General Education: None
Diversity: None
Bachelor of Arts: None
Effective: Fall 2014
Prerequisite: MATSE 201 orCHEM 112 andMATH 230 orMATH 231

Note : Class size, frequency of offering, and evaluation methods will vary by location and instructor. For these details check the specific course syllabus.


Look up course abbreviations

Course descriptions are stored in LionPATH, the University-wide student information system. Please visit the LionPATH Course Catalog to access current course descriptions. At that point, you will be leaving the University Bulletin website.

Skip Popular Searches
  1. Bachelor of Arts Degree Requirements
  2. General Education: United States Cultures and International Cultures
  3. Course Index
  4. Graduate Degree Programs Bulletin
  5. General Education: Arts
  6. General Education: Humanities
  7. General Education: Health and Physical Activity
  8. General Education: Natural Sciences
  9. General Education: Social and Behavioral Sciences
  10. General Education: Writing/Speaking